10. Use hard copies to proofread. Errors jump out on paper in a way they don't onscreen.
9. Read your work with a ruler.
8. Read your work aloud.
7. Read your work backwards (start at the end).
6. Be extra careful of missing small words: a, an, the, or.
5. Use a more sophisticated grammar/spell check program than the one available in Word.
I like WhiteSmoke.
4. For major revisions, edit your work in a new document.
3. Omit needless words. From The Elements of Style:
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2. Reckless comma usage leads to choppiness and difficult reading. Commit some time to learning the difference between a punctuation rule and a style choice. Start here. And watch this. Don't believe the old adage about using commas where you'd pause for breath - you'll end up overpunctuating.
1. The most misspelled word? Your - You’re (one solution: stop using you're altogether. Use only you are.)